Description

2,4-Dichloro-6-Fluoropyrimidine is a versatile halogenated pyrimidine building block of significant importance in advanced organic synthesis. Its core value lies in its high reactivity, where the chlorine and fluorine atoms serve as excellent leaving groups, enabling selective nucleophilic substitution reactions to create complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, including kinase inhibitors, antiviral agents, and anticancer compounds.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the pyrimidine core for biological activity.
• Material Science: Serves as a building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new heterocyclic chemistry and creating specialized chemical libraries.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) to produce tailored molecules for client projects.

Basic Information

Product Name	2,4-Dichloro-6-Fluoropyrimidine
CAS No.	3833-57-6
Molecular Formula	C4HCl2FN2
Molecular Weight	166.96 g/mol
Synonyms	6-Fluoro-2,4-dichloropyrimidine; 2,4-Dichloro-6-fluoropyrimidine; 2,4-Dichloro-6-fluoro-1,3-diazine; Fluoropyrimidine derivative; Pyrimidine, 2,4-dichloro-6-fluoro-; 3833-57-6; 6-Fluoro-2,4-dichloro-1,3-diazine
EINECS	223-337-5

Quality Control

Our 2,4-Dichloro-6-Fluoropyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.