Description

4,6-Dichloro-2-Fluoropyrimidine is a versatile halogenated pyrimidine building block of significant importance in modern synthetic chemistry. Its value lies in its reactive sites, which allow for selective functionalization, making it a critical intermediate for constructing complex molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its pyrimidine core.
• Chemical Research & Development: Serves as a fundamental building block in medicinal chemistry and material science for creating novel molecular libraries.
• Ligand and Catalyst Preparation: Utilized in the preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Fluorinated Compound Production: Acts as a source of a fluorinated heterocycle for introducing fluorine atoms into target molecules to modulate their properties.

Basic Information

Product Name	4,6-Dichloro-2-Fluoropyrimidine
CAS No.	3824-45-1
Molecular Formula	C4HCl2FN2
Molecular Weight	166.96 g/mol
Synonyms	2-Fluoro-4,6-dichloropyrimidine; 4,6-Dichloro-2-fluoropyrimidine; 2-Fluoro-4,6-dichloro-1,3-diazine; Fluoropyrimidine, 4,6-dichloro-2-; Pyrimidine, 4,6-dichloro-2-fluoro-; 3824-45-1 (CAS); 4,6-Dichloro-2-fluoro-1,3-diazine
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-2-Fluoropyrimidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.