Description

H-Asp(Gly-Oh)-Oh CAS NO 3790-52-1 is a high-purity, protected dipeptide derivative, specifically N-(tert-Butoxycarbonyl)-L-aspartylglycine, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a controlled, reactive pathway for constructing complex peptide sequences, particularly in solid-phase peptide synthesis (SPPS) and the development of novel bioactive compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality raw materials for drug discovery and development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex therapeutic peptides and peptidomimetics.
• Solid-Phase Peptide Synthesis (SPPS): Used as a protected aspartylglycine unit for the controlled elongation of peptide chains.
• Bioconjugation & Linker Chemistry: Serves as a spacer or component in the design of drug conjugates and bioconjugates.
• Research & Development: Fundamental reagent in academic and industrial R&D for exploring new peptide-based drugs and biochemical tools.
• Fine Chemical Synthesis: Intermediate in the custom synthesis of specialized organic compounds and chiral molecules.

Basic Information

Product Name	H-Asp(Gly-Oh)-Oh
CAS No.	3790-52-1
Molecular Formula	C11H18N2O7
Molecular Weight	290.27 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-aspartylglycine; Boc-Asp-Gly-OH; Boc-L-Asp-Gly-OH; (2S)-2-[[(2S)-4-[(2-Methylpropan-2-yl)oxy]-2-(carboxymethylamino)-4-oxobutanoyl]amino]acetic acid; Boc-Aspartylglycine; N-Boc-L-aspartylglycine; L-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, glycyl-; Protected Aspartylglycine Dipeptide
EINECS	Contact for details

Quality Control

Our H-Asp(Gly-Oh)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques like HPLC and NMR. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	-20.0° to -24.0° (c=1 in DMF)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.2%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.