Description

D-Glucuronamide is a high-purity biochemical derivative of D-glucuronic acid, a key metabolite in mammalian detoxification pathways. This compound serves as a crucial advanced intermediate and reference standard in pharmaceutical research and diagnostic development. It is primarily utilized by research institutions, pharmaceutical R&D labs, and manufacturers of diagnostic reagents for applications in enzymology, metabolic studies, and analytical method validation.

Application

• Pharmaceutical Intermediate: Used in the synthesis of more complex glycosylated compounds and potential drug candidates targeting metabolic enzymes.
• Biochemical Research: Serves as a substrate or standard in enzymatic assays, particularly for studying β-glucuronidase activity and glucuronidation pathways.
• Diagnostic Reagent Manufacturing: Employed as a key component in the production of clinical diagnostic kits for liver function and detoxification capacity tests.
• Reference Standard: Provides a high-purity calibrant for analytical methods like HPLC and LC-MS in pharmacokinetic and metabolomic studies.
• Nutritional Science Research: Investigated for its role in conjugate formation and its potential bioavailability in related nutritional compounds.

Basic Information

Item	Detail
Product Name	D-Glucuronamide
CAS No.	3789-97-7
Molecular Formula	C6H11NO6
Molecular Weight	193.16 g/mol
Synonyms	D-Glucuronic acid amide; Glucuronamide; (2S,3S,4S,5R)-2,3,4,5-Tetrahydroxy-6-oxohexanamide; 6-Carbamoyl-D-glucose; D-Glucopyranuronic acid amide
EINECS	223-267-1

Quality Control

Our D-Glucuronamide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and specific tests for related substances and residual solvents. A Certificate of Analysis (COA) detailing all results is provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store in a cool, dry place at controlled room temperature (15-25°C). For long-term stability, consider storage under an inert atmosphere or with desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.