Description

n-Acetyl-L-Phenylalanyl-3,5-Diiodo-L-Tyrosine is a chemically modified dipeptide derivative, specifically engineered for advanced research and development applications. This compound is valued for its unique structural features, including the acetylated N-terminus and halogenated tyrosine residue, which make it a critical intermediate in the synthesis of specialized peptides and biochemical probes. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and academic institutions engaged in peptide chemistry, hormone analog development, and radiopharmaceutical precursor studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel peptide-based therapeutics and hormone analogs.
• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies and receptor binding assays due to its iodinated tyrosine moiety.
• Radiopharmaceutical Precursor: The diiodotyrosine structure provides a platform for the development of iodine-labeled compounds for diagnostic imaging.
• Peptide Chemistry: An important intermediate for constructing complex peptides with specific modifications for structure-activity relationship (SAR) studies.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	n-Acetyl-L-Phenylalanyl-3,5-Diiodo-L-Tyrosine
CAS No.	3786-08-1
Molecular Formula	C20H20I2N2O5
Molecular Weight	646.19 g/mol
Synonyms	Ac-Phe-Tyr(3,5-I2)-OH; N-Acetyl-L-phenylalanyl-3,5-diiodo-L-tyrosine; L-Tyrosine, N-acetyl-3,5-diiodo-, phenylalanyl-; Acetylphenylalanyldiiodotyrosine; N-Ac-Phe-Tyr(3,5-I2); 3,5-Diiodotyrosine, N-acetyl-, phenylalanyl derivative; N-Acetylphenylalanyl-3,5-diiodotyrosine
EINECS	Contact for details

Quality Control

Our n-Acetyl-L-Phenylalanyl-3,5-Diiodo-L-Tyrosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and heavy metals. We provide Certificates of Analysis (COA) with detailed specifications for traceability and compliance. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.