Description

2,4,6-Trichloropyrimidine is a versatile halogenated heterocyclic building block of significant importance in advanced organic synthesis. Its value lies in the high reactivity of its chlorine atoms, enabling selective nucleophilic substitution to create complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable, high-purity intermediate for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and kinase inhibitor drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyrimidine core provides essential bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel nitrogen-containing ligands for metal catalysis and coordination chemistry.
• Material Science: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or monomers for specialty polymers.
• Custom Synthesis & Research: A fundamental reagent in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	2,4,6-Trichloropyrimidine
CAS No.	3764-01-0
Molecular Formula	C4HCl3N2
Molecular Weight	183.42 g/mol
Synonyms	2,4,6-Trichloro-1,3-diazine; s-Trichloropyrimidine; Pyrimidine, 2,4,6-trichloro-; NSC 402868; 1,3-Diazine, 2,4,6-trichloro-; Trichloropyrimidine
EINECS	223-176-9

Quality Control

Our 2,4,6-Trichloropyrimidine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure it meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles. We support compliance with REACH and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and moisture. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.