Description

4,6-Dichloro-2-(Chloromethyl)-5-Methylpyrimidine is a versatile halogenated pyrimidine building block of significant importance in advanced organic synthesis. Its reactive chloromethyl and chloro substituents make it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of specialized heterocyclic dyes and optical materials.
• Material Science: Potential monomer or cross-linking agent for creating polymers with specific thermal or chemical properties.

Basic Information

Product Name	4,6-Dichloro-2-(Chloromethyl)-5-Methylpyrimidine
CAS No.	3764-00-9
Molecular Formula	C6H5Cl3N2
Molecular Weight	211.47 g/mol
Synonyms	2-(Chloromethyl)-4,6-dichloro-5-methylpyrimidine; 5-Methyl-4,6-dichloro-2-chloromethylpyrimidine; 4,6-Dichloro-5-methyl-2-(chloromethyl)pyrimidine; 2-Chloromethyl-4,6-dichloro-5-methylpyrimidine; NSC 403169; Pyrimidine, 4,6-dichloro-2-(chloromethyl)-5-methyl-
EINECS	223-179-5

Quality Control

Our production of 4,6-Dichloro-2-(Chloromethyl)-5-Methylpyrimidine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. A detailed Certificate of Analysis (COA) confirming specifications for identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.