Description

5-Chloro-6-Hydroxy-5-Nitro-Dihydro-Pyrimidine-2,4-Dione is a specialized heterocyclic organic compound that serves as a critical synthetic intermediate in advanced chemical manufacturing. Its unique nitro and chloro-substituted pyrimidine-dione structure makes it a valuable precursor for developing active pharmaceutical ingredients (APIs) and fine chemicals. This high-purity intermediate is essential for research and production facilities in the pharmaceutical, agrochemical, and specialty chemical sectors seeking reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel nucleoside analogs and potential antiviral or anticancer agents.
• Agrochemical Research: Used in the development of new herbicides and plant growth regulators, leveraging its reactive nitro and chloro functional groups.
• Fine Chemical Synthesis: Serves as a precursor for creating complex dyes, pigments, and other specialty organic compounds.
• Biochemical Research: Employed in academic and industrial R&D for studying enzyme inhibitors and modifying nucleic acid structures.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers with unique properties.

Basic Information

Product Name	5-Chloro-6-Hydroxy-5-Nitro-Dihydro-Pyrimidine-2,4-Dione
CAS No.	3749-49-3
Molecular Formula	C4H2ClN3O5
Molecular Weight	207.53 g/mol
Synonyms	5-Chloro-6-hydroxy-5-nitropyrimidine-2,4(1H,3H)-dione; 5-Chloro-5-nitro-6-hydroxyuracil; 5-Nitro-5-chloro-6-hydroxyuracil; 5-Chloro-5-nitro-6-hydroxypyrimidine-2,4-dione; 5-Chloro-6-hydroxy-5-nitrobarbituric acid; 3749-49-3; 5-Chloro-5-nitro-6-hydroxydihydropyrimidine-2,4-dione
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-6-Hydroxy-5-Nitro-Dihydro-Pyrimidine-2,4-Dione is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent lot-to-lot quality. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.