Description

n-(4-Acetamido-2,6-Difluoro-Phenyl)Acetamide is a high-purity, difluorinated aromatic acetamide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stable, functionalized core for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific fluorine and amide functionalities into their target structures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and anti-cancer therapies.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators where the difluoroacetamide moiety enhances biological activity and metabolic stability.
• Material Science Precursor: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials that require fluorinated aromatic components for improved performance.
• Chemical Research & Development: Serves as a versatile scaffold in academic and industrial R&D for exploring new chemical reactions and creating libraries of compounds for high-throughput screening.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing advanced colorants and fluorescent markers with specific light-absorption properties.

Basic Information

Product Name	n-(4-Acetamido-2,6-Difluoro-Phenyl)Acetamide
CAS No.	3743-91-7
Molecular Formula	C10H10F2N2O2
Molecular Weight	228.20 g/mol
Synonyms	N1,N4-Bis(acetyl)-2,6-difluorobenzene-1,4-diamine; 2',6'-Difluoro-4'-aminoacetanilide, Diacetyl Derivative; 2,6-Difluoro-4-acetamidoacetanilide; 1,4-Diacetamido-2,6-difluorobenzene; 4-Acetamido-2,6-difluoroacetanilide; 2,6-Difluoro-N1,N4-diacetylbenzene-1,4-diamine; 3743-91-7; DFAA Diacetamide
EINECS	Contact for details

Quality Control

Our n-(4-Acetamido-2,6-Difluoro-Phenyl)Acetamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.