Description

Cyclo(-Phe-Pro) CAS NO 3705-26-8 is a high-purity diketopiperazine (DKP) derivative, a cyclic dipeptide formed from phenylalanine and proline. This compound is valued for its structural role as a key building block and scaffold in advanced pharmaceutical research and peptide chemistry. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors developing novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of novel drug candidates and bioactive molecules.
• Peptide Mimetics Research: Used in medicinal chemistry to develop stable, metabolically resistant peptide analogs.
• Chemical Biology Probe: Acts as a tool compound for studying enzyme inhibition and protein-protein interactions.
• Fine Chemical Synthesis: Employed as a chiral building block in asymmetric synthesis and catalyst development.
• Cosmetic & Dermatological Actives: Investigated for potential use in anti-aging and skin-conditioning formulations.
• Academic & Industrial R&D: Essential for basic research in organic chemistry, biochemistry, and pharmacology.

Basic Information

Product Name	Cyclo(-Phe-Pro)
CAS No.	3705-26-8
Molecular Formula	C14H16N2O2
Molecular Weight	244.29 g/mol
Synonyms	Cyclo(L-phenylalanyl-L-prolyl); Cyclo(Phe-Pro); L-Phenylalanyl-L-proline anhydride; 3-Benzyl-6-(2-carboxyethyl)-2,5-piperazinedione; DKPs; 2,5-Diketopiperazine; 3-Benzyl-6-(2-carboxyethyl)piperazine-2,5-dione; (3S,6S)-3-Benzylpiperazine-2,5-dione
EINECS	223-055-1

Quality Control

Our Cyclo(-Phe-Pro) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (L, L isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.