Description

Bis(Trifluoromethyl) Aniline is a high-value fluorinated aromatic amine building block characterized by its two electron-withdrawing trifluoromethyl groups. This unique structure imparts significant chemical stability and lipophilicity, making it a critical intermediate for advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients. Its properties also make it valuable in materials science for developing specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas requiring enhanced metabolic stability and membrane permeability.
• Agrochemical Active Ingredient Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the CF3 groups contribute to biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting technologies, improving performance and stability.
• Specialty Polymer & Resin Modifier: Incorporated to enhance the chemical resistance, thermal stability, and surface properties of high-performance polymers.
• Organic Synthesis & Catalysis Ligand: Utilized as a precursor for complex ligands in catalytic systems and in general organic synthesis for introducing fluorinated aniline motifs.
• Dye & Pigment Intermediate: Employed in the production of specialized, light-fast colorants for demanding industrial applications.

Basic Information

Item	Detail
Product Name	Bis(Trifluoromethyl) Aniline
CAS No.	3700-19-4
Molecular Formula	C8H5F6N
Molecular Weight	229.12 g/mol
Synonyms	2,4-Bis(trifluoromethyl)aniline; 2,4-Bis(trifluoromethyl)benzenamine; α,α,α,α',α',α'-Hexafluoro-2,4-xylidine; 2-Amino-1,3-bis(trifluoromethyl)benzene; 2,4-Di(trifluoromethyl)aniline; 2,4-Bis(trifluoromethyl)phenylamine; 2,4-(CF3)2C6H3NH2
EINECS	223-045-3

Quality Control

Our production of Bis(Trifluoromethyl) Aniline adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific impurity profiles is provided with every shipment. We support compliance with global regulatory frameworks, and custom purity grades, including research and pharmaceutical intermediates, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its amine functionality and fluoride content, it should be stored separately from strong acids, strong oxidizing agents, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline mass
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.