Description

2-Oxo-4-(5-Nitro-2-Furyl)-6-Methyl-1,2,3,4-Tetrahydropyrimidine-5-Carboxylic Acid Methyl Ester is a specialized heterocyclic compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its unique molecular scaffold, which combines nitro-furan and tetrahydropyrimidine moieties, making it a versatile building block for pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting infectious diseases or possessing antimicrobial properties.
• Agrochemical Research: Used in the development of novel fungicides or herbicides, leveraging the bioactive nitro-furyl group.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme inhibition or cellular pathways.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to construct complex heterocyclic systems for material science or specialty chemicals.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for methodological studies in heterocyclic chemistry and medicinal chemistry programs.

Basic Information

Product Name	2-Oxo-4-(5-Nitro-2-Furyl)-6-Methyl-1,2,3,4-Tetrahydropyrimidine-5-Carboxylic Acid Methyl Ester
CAS No.	3690-88-8
Molecular Formula	C11H9N3O6
Molecular Weight	279.21 g/mol
Synonyms	Methyl 2-oxo-4-(5-nitro-2-furyl)-6-methyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 5-Carbomethoxy-4-(5-nitro-2-furyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-one; 4-(5-Nitro-2-furyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid methyl ester; 5-Methoxycarbonyl-4-(5-nitro-2-furyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-one; Nitrofuryl dihydropyrimidinone ester; 3690-88-8; 4-(5-Nitro-2-furanyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 2-Oxo-4-(5-Nitro-2-Furyl)-6-Methyl-1,2,3,4-Tetrahydropyrimidine-5-Carboxylic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data (HPLC, NMR, IR) are provided to guarantee traceability and batch-to-batch reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.