Description

Boc-Gly-Onp is a specialized amino acid derivative where the glycine amino group is protected by a tert-butoxycarbonyl (Boc) group and activated by an o-nitrophenyl (Onp) ester. This compound is a crucial reagent in peptide synthesis, offering a reactive ester for efficient coupling under mild conditions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries for the controlled synthesis of peptides and peptide conjugates.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an activated ester derivative for the efficient incorporation of glycine into peptide chains.
• Solution-Phase Peptide Synthesis: For the synthesis of short peptides, peptide fragments, and modified peptides in solution.
• Bioconjugation: Used to attach glycine or peptide sequences to other molecules like proteins, polymers, or surfaces.
• Pharmaceutical Intermediate: Serves as a key building block in the research and development of peptide-based active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Employed in the synthesis of labeled peptides for studying biological processes and interactions.
• Material Science: For the synthesis of peptide-functionalized materials and hydrogels.

Basic Information

Product Name	Boc-Gly-Onp
CAS No.	3655-05-8
Molecular Formula	C₁₃H₁₆N₂O₆
Molecular Weight	296.28 g/mol
Synonyms	N-(tert-Butoxycarbonyl)glycine 4-nitrophenyl ester; Boc-Glycine 4-nitrophenyl ester; N-Boc-glycine 4-nitrophenyl ester; Glycine, N-[(1,1-dimethylethoxy)carbonyl]-, 4-nitrophenyl ester; 2-[(tert-Butoxycarbonyl)amino]acetic acid 4-nitrophenyl ester; Boc-Gly-ONp; Boc-Gly-OPh(NO2)
EINECS	Contact for details

Quality Control

Our Boc-Gly-Onp is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality commitment supports applications in research and cGMP-compliant pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.