Description

L-[35S]Methionine is a radiolabeled amino acid essential for metabolic and protein synthesis studies. This compound is critical for researchers requiring high-specific-activity tracers to investigate cellular processes with precision. It is primarily used by life science researchers, pharmaceutical developers, and diagnostic manufacturers in applications such as autoradiography, protein labeling, and metabolic pathway analysis.

Application

• Protein Synthesis & Metabolic Labeling: Used as a tracer to study the kinetics and localization of newly synthesized proteins in cell cultures and animal models.
• Autoradiography & Imaging: Enables visualization of methionine incorporation and distribution in tissues and gels for biomedical research.
• Pulse-Chase Experiments: Essential for tracking protein turnover, degradation rates, and intracellular trafficking over time.
• Diagnostic Probe Development: Serves as a precursor for developing radiolabeled probes for PET imaging and other diagnostic techniques.
• Cell Proliferation & Translational Research: Utilized to assess cellular growth and metabolic activity in cancer research and drug discovery.
• Biochemical Pathway Analysis: Investigates methionine metabolism, including transmethylation and transsulfuration pathways.

Basic Information

Product Name	L-[35S]Methionine
CAS No.	3654-96-4
Molecular Formula	C5H1135S NO2
Molecular Weight	~165.2 g/mol (for 35S)
Synonyms	(S)-2-Amino-4-((35S)sulfanyl)butanoic acid; L-Methionine (35S); [35S]-L-Methionine; Methionine-S-35; Radiolabeled L-Methionine; 35S-Met; S-35 Methionine; L-Methionine, labeled with sulfur-35
EINECS	Contact for details

Quality Control

Our L-[35S]Methionine is produced and handled under strict quality systems to ensure batch-to-batch consistency and reliability for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing radiochemical purity, specific activity, chemical purity, and sterility (where applicable). We adhere to relevant guidelines for the handling of radioactive materials to ensure product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C. Due to its sensitivity, this product must be kept strictly light-sensitive (protect from all light exposure) and is easily oxidized (store under inert atmosphere). Appropriate shielding and handling procedures for radioactive materials must be followed at all times.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Identification (HPLC/Radio-TLC)	Conforms
Radiochemical Purity	≥ 95%
Specific Activity	> 1000 Ci/mmol (Contact for exact value)
Chemical Purity (HPLC)	≥ 98%
Solvent	Aqueous solution (specified per batch)
Radionuclidic Purity	≥ 99% 35S

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.