Description

Homocysteine Thiolactone is a key heterocyclic organosulfur compound derived from the metabolism of the essential amino acid methionine. This versatile intermediate is of significant interest in biochemical research and pharmaceutical development due to its role in homocysteine metabolism and associated biological pathways. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical, and diagnostic industries for applications ranging from metabolic studies to the synthesis of more complex molecules.

Application

• Biochemical Research: A critical intermediate for studying homocysteine metabolism, hyperhomocysteinemia, and related cardiovascular or neurological conditions.
• Pharmaceutical Synthesis: Serves as a versatile building block for the development of novel therapeutic agents and enzyme inhibitors targeting metabolic pathways.
• Diagnostic Reagent Production: Used in the formulation of assay kits and calibrators for the quantitative measurement of homocysteine and related metabolites in clinical settings.
• Nutritional Science Studies: Employed in research investigating the impact of B-vitamin deficiencies (B6, B12, folate) on homocysteine cycle dysregulation.
• Reference Standard: Acts as a high-purity analytical standard for quality control in pharmaceutical manufacturing and clinical laboratory testing.

Basic Information

Product Name	Homocysteine Thiolactone
CAS No.	3622-59-1
Molecular Formula	C5H7NO2S
Molecular Weight	145.18 g/mol
Synonyms	L-Homocysteine thiolactone; 2-Amino-4,5-dihydro-4-thiazolecarboxylic acid; DL-Homocysteine thiolactone; Homocysteine thiolactone hydrochloride; Homocysteine thiolactone HCL; Hcy-thiolactone; 2-Amino-4-mercaptobutyric acid γ-lactone; Thiomorpholinone derivative
EINECS	222-828-5

Quality Control

Our Homocysteine Thiolactone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial use. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.