Description

(S)-(+)-n-Acetyl-Serine Methyl Ester CAS NO 3619-01-0 is a high-purity, enantiomerically pure derivative of the amino acid serine, serving as a critical chiral building block in advanced organic synthesis. Its primary value lies in providing a protected, stereochemically defined serine moiety, enabling the efficient construction of complex peptides and bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical, biotechnology, and fine chemical industries, particularly for the synthesis of peptide-based drugs, enzyme inhibitors, and other sophisticated chiral intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of peptide-based therapeutics, enzyme inhibitors, and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate protected serine residues with defined stereochemistry.
• Bioconjugation & Probe Development: Serves as a starting material for creating fluorescent probes, affinity labels, and other bioconjugates for biochemical research.
• Chemical Biology Research: Employed in the study of enzyme mechanisms, protein-protein interactions, and metabolic pathways.
• Fine Chemical Synthesis: A versatile building block for the preparation of complex natural products, macrocycles, and other specialty chemicals.
• Asymmetric Catalysis: Can be used as a chiral auxiliary or ligand precursor in asymmetric synthesis.

Basic Information

Product Name	(S)-(+)-n-Acetyl-Serine Methyl Ester
CAS No.	3619-01-0
Molecular Formula	C6H11NO4
Molecular Weight	161.16 g/mol
Synonyms	(S)-N-Acetylserine Methyl Ester; (S)-(+)-2-Acetamido-3-hydroxypropanoic Acid Methyl Ester; L-N-Acetylserine Methyl Ester; Methyl (S)-2-acetamido-3-hydroxypropanoate; Methyl L-N-acetylserinate; Ac-Ser-OMe; N-Acetyl-L-serine methyl ester; (S)-2-(Acetylamino)-3-hydroxypropionic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our (S)-(+)-n-Acetyl-Serine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.