Description

tert-Butoxycarbonylamino-Phenyl-Acetic Acid is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical building block for the introduction of phenylglycine moieties under mild conditions, enabling the construction of complex molecules with high fidelity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel peptides, active pharmaceutical ingredients (APIs), and other fine chemicals.

Application

• Peptide Synthesis: A key protected intermediate for the solid-phase and solution-phase synthesis of peptides containing phenylglycine residues.
• Pharmaceutical Intermediates: Used in the research and production of various drug candidates, particularly in medicinal chemistry for structure-activity relationship (SAR) studies.
• Protecting Group Chemistry: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for the amino function, allowing for selective deprotection in multi-step syntheses.
• Bioconjugation: Employed in the preparation of modified biomolecules and linker systems for targeted drug delivery and diagnostic applications.
• Chemical Biology Research: Utilized as a tool compound to probe biological pathways and enzyme functions.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing bespoke organic molecules.

Basic Information

Product Name	tert-Butoxycarbonylamino-Phenyl-Acetic Acid
CAS No.	3601-66-9
Molecular Formula	C₁₃H₁₇NO₄
Molecular Weight	251.28 g/mol
Synonyms	Boc-Phenylglycine-OH; N-(tert-Butoxycarbonyl)-2-phenylglycine; (2-((tert-Butoxycarbonyl)amino)-2-phenylacetic acid; N-Boc-α-phenylglycine; Boc-Pheg-OH; N-Boc-phenylglycine; BOC-PHG-OH; 2-[(tert-Butoxycarbonyl)amino]-2-phenylacetic acid
EINECS	Contact for details

Quality Control

Our tert-Butoxycarbonylamino-Phenyl-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), chiral purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.