Description

ε-Pyridoxyllysine is a stable, covalently bound adduct formed between pyridoxal 5'-phosphate (PLP) and lysine residues, serving as a key biochemical marker for vitamin B6 status and protein modification studies. This compound is essential for researchers and manufacturers requiring precise tools to investigate PLP-dependent enzymatic mechanisms and assess functional vitamin B6 levels in biological systems. It is primarily utilized in the life sciences sector for analytical method development, clinical diagnostics, and advanced biochemical research.

Application

• Biochemical Research: Used as a reference standard and probe in studies of vitamin B6 metabolism, enzyme cofactor binding, and transamination reactions.
• Clinical Diagnostics: Serves as a critical calibrator and control in HPLC and LC-MS/MS assays to quantify vitamin B6 sufficiency and related metabolic disorders.
• Pharmaceutical Development: Employed in stability studies and analytical method validation for drugs or nutraceuticals involving vitamin B6 pathways.
• Food & Nutrition Science: Applied in research to analyze protein-bound B6 vitamers and assess the nutritional bioavailability of vitamin B6 in fortified foods and supplements.
• Proteomics & Metabolomics: Acts as a specific marker for identifying and quantifying PLP-modified proteins in complex biological samples.

Basic Information

Product Name	ε-Pyridoxyllysine
CAS No.	3564-92-9
Molecular Formula	C14H21N3O5
Molecular Weight	311.34 g/mol
Synonyms	N6-(Pyridoxyl)-L-lysine; N(6)-Pyridoxyllysine; L-Lysine, N6-(3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinyl)methyl]-; Pyridoxyllysine; PLP-Lysine Adduct; Vitamin B6-Lysine Conjugate; ε-Pyridoxyllysine; 5'-Pyridoxyllysine
EINECS	Contact for details

Quality Control

Our ε-Pyridoxyllysine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and diagnostic applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.