Description

Z-Tyr-Onp is a specialized chemical derivative of tyrosine, commonly utilized as a protected amino acid building block in peptide synthesis. This compound is critical for researchers and manufacturers requiring high-purity intermediates to ensure the fidelity and yield of complex peptide sequences. It is primarily employed in pharmaceutical R&D, biotechnology, and fine chemical synthesis for developing novel therapeutic agents and biochemical tools.

Application

• Peptide Synthesis: Serves as a key protected tyrosine derivative for solid-phase and solution-phase peptide assembly.
• Pharmaceutical Intermediates: Used in the research and production of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: Acts as a reagent for attaching peptides to other molecules, surfaces, or carriers in diagnostic and therapeutic applications.
• Biochemical Research: Employed as a standard or reagent in studies of enzyme kinetics, protein interactions, and signal transduction pathways.
• Protecting Group Chemistry: Utilized in organic synthesis methodologies where the Onp (o-Nitrophenyl) group provides specific cleavage and deprotection advantages.

Basic Information

Product Name	Z-Tyr-Onp
CAS No.	3556-56-7
Molecular Formula	C23H20N2O7
Molecular Weight	436.42 g/mol
Synonyms	N-Carbobenzyloxy-L-tyrosine 4-nitrophenyl ester; Z-L-Tyrosine 4-nitrophenyl ester; Z-Tyrosine p-nitrophenyl ester; Nα-Cbz-L-tyrosine p-nitrophenyl ester; Benzyloxycarbonyl-L-tyrosine 4-nitrophenyl ester; CBZ-L-Tyrosine ONP ester; (S)-2-(((Benzyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoic acid 4-nitrophenyl ester
EINECS	Contact for details

Quality Control

Our Z-Tyr-Onp is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	-10.0° to -15.0° (c=1 in DMF)
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.