Description

Cyclobradykinin is a synthetic cyclic peptide analog of bradykinin, a potent vasoactive hormone. This compound is of significant interest in biochemical and pharmacological research for studying receptor interactions and signal transduction pathways. It serves as a critical tool for researchers in pharmaceutical development, cardiovascular research, and neurobiology, enabling the exploration of inflammation, pain, and blood pressure regulation mechanisms.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies targeting bradykinin B1 and B2 receptors.
• Drug Discovery & Development: A key intermediate or biochemical tool in the development of novel anti-inflammatory, analgesic, or antihypertensive therapeutics.
• Biochemical Assays: Employed in enzyme-linked immunosorbent assays (ELISA), radioimmunoassays (RIA), and other in vitro diagnostic tests to calibrate and validate results.
• Academic & Institutional Research: Supports fundamental research in physiology, vascular biology, and neuropeptide signaling at universities and research institutes.
• Peptide Chemistry Studies: Serves as a model compound for studying the structure-activity relationships (SAR) of cyclic peptides and their stability.

Basic Information

Product Name	Cyclobradykinin
CAS No.	3522-46-1
Molecular Formula	C50H73N15O11
Molecular Weight	1044.2 g/mol
Synonyms	Cyclo(-D-Phe7-Pro2-Gly3-Phe5-Ser6-D-Phe7)-Bradykinin; Cyclic Bradykinin; H-Cyclo[D-Phe-Pro-Gly-Phe-Ser-D-Phe]OH; Bradykinin, cyclic (6->1)-lactam; Cyclo(D-Phe-Pro-Gly-Phe-Ser-D-Phe); [Cyclo(D-Phe7, Pro2)]Bradykinin
EINECS	Contact for details

Quality Control

Our Cyclobradykinin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in DMSO, acetic acid; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.