Description

D-Phe-L-Val-Oh is a high-purity dipeptide building block, specifically the C-terminal carboxylic acid derivative of the phenylalanine-valine sequence. This compound is critical for the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control for advanced research and development. It serves as an essential intermediate for pharmaceutical chemists and biochemists in drug discovery, proteomics research, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the solid-phase and solution-phase synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Protease Substrate Analog: Used in biochemical research to study enzyme kinetics, specificity, and inhibition mechanisms of proteolytic enzymes.
• Peptidomimetic Design: Serves as a core scaffold for developing metabolically stable peptide analogs with enhanced bioavailability.
• Bioconjugation: Utilized in the preparation of peptide-protein conjugates for diagnostic assays and targeted drug delivery systems.
• Academic & Industrial R&D: Fundamental reagent in laboratories focused on medicinal chemistry, structural biology, and peptide science.
• Reference Standard: Employed as a chromatographic standard for quality control and analytical method development in peptide manufacturing.

Basic Information

Product Name	D-Phe-L-Val-Oh
CAS No.	3496-45-5
Molecular Formula	C14H20N2O3
Molecular Weight	264.32 g/mol
Synonyms	D-Phenylalanyl-L-valine; (R)-2-((S)-2-Amino-3-methylbutanamido)-3-phenylpropanoic acid; H-D-Phe-L-Val-OH; D-Phe-Val; D-Phenylalanine-L-valine; Valine, N-[(1R)-1-carboxy-2-phenylethyl]-L-; Benzenepropanoic acid, α-[[(1S)-1-carboxy-2-methylpropyl]amino]-, (αR)-
EINECS	Contact for details

Quality Control

Our D-Phe-L-Val-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% de
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.2%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.