Description

H-Gly-His-Oh Hcl is a high-purity dipeptide derivative, specifically the hydrochloride salt of glycyl-L-histidine. This compound serves as a critical building block and biochemical reagent in advanced research and synthesis. It is essential for pharmaceutical development, peptide chemistry, and life science applications where precise molecular structure and purity are paramount. Global B2B buyers rely on this material for its consistent quality and reliable performance in demanding processes.

Application

• Pharmaceutical Intermediate: Used in the research and synthesis of novel therapeutic peptides and active pharmaceutical ingredients (APIs).
• Biochemical Research: Serves as a standard, substrate, or precursor in enzymatic studies and metabolic pathway investigations.
• Peptide Synthesis: A key protected dipeptide building block for solid-phase and solution-phase peptide chain assembly.
• Nutraceutical Development: Investigated for use in specialized nutritional supplements and bioactive formulations.
• Cosmetic Peptides: Explored as a component in advanced skincare and anti-aging cosmetic formulations.
• Cell Culture Media: Potentially used as a component in specialized cell culture and fermentation media.

Basic Information

Product Name	H-Gly-His-Oh Hcl
CAS No.	3486-76-8
Molecular Formula	C8H15N5O3 • HCl
Molecular Weight	281.70 g/mol (Free base: 245.24)
Synonyms	Glycyl-L-histidine hydrochloride; H-Gly-His-OH • HCl; Gly-His dipeptide HCl; L-Histidylglycine hydrochloride; N-Glycyl-L-histidine hydrochloride; 2-[[(2S)-2-Amino-1-hydroxy-3-(1H-imidazol-5-yl)propylidene]amino]acetic acid hydrochloride; G-H dipeptide HCl
EINECS	Contact for details

Quality Control

Our H-Gly-His-Oh Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets stringent specifications for research and industrial use. Certificates of Analysis (COA) with full traceability are provided to guarantee supply reliability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.