Description

n-α-Trityl-L-Valine Diethylamine is a specialized, protected amino acid derivative used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the development of complex peptides and active pharmaceutical ingredients (APIs). It is primarily utilized in pharmaceutical R&D, process chemistry, and fine chemical production where precise molecular control is paramount.

Application

• Peptide Synthesis Intermediate: Serves as a key protected valine derivative in solid-phase and solution-phase peptide synthesis, particularly for complex or long-chain peptides.
• Pharmaceutical Research & Development: Used as a building block in the discovery and development of novel therapeutic agents, including peptide-based drugs.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Fine Chemical Production: Acts as a high-value intermediate in the manufacture of specialty chemicals and custom synthesis projects.
• Bioconjugation & Labeling Chemistry: Utilized in the preparation of modified peptides for diagnostic or biochemical research applications.
• Academic & Institutional Research: A valuable reagent for universities and research institutes conducting studies in organic chemistry, medicinal chemistry, and biochemistry.

Basic Information

Product Name	n-α-Trityl-L-Valine Diethylamine
CAS No.	3485-55-0
Molecular Formula	C30H38N2O2
Molecular Weight	458.64 g/mol
Synonyms	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valine; Fmoc-L-Valine; Fmoc-Val-OH; N-(9-Fluorenylmethoxycarbonyl)-L-valine; (2S)-2-[(9H-Fluoren-9-ylmethoxy)formamido]-3-methylbutanoic acid; N-α-Fmoc-L-valine; L-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-; Fmoc-Valine
EINECS	Contact for details

Quality Control

Our n-α-Trityl-L-Valine Diethylamine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and chiral purity, to meet the stringent requirements of pharmaceutical and research applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.