Description

Glycylglycinamide Hydrobromide is a high-purity, protected dipeptide building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the production of complex peptides and peptidomimetics, offering precise control over molecular structure. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery, medicinal chemistry, and the development of bioactive compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the solid-phase and solution-phase synthesis of novel therapeutic peptides.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new drug candidates and enzyme inhibitors.
• Bioconjugation: Serves as a spacer or linker molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Protease Substrate Analog: Employed in biochemical assays to study protease enzyme activity and mechanism.
• Chemical Biology Tool: Utilized for probing protein-protein interactions and cellular signaling pathways.
• Custom Peptide Synthesis: A fundamental component for contract research organizations (CROs) and CDMOs producing custom peptides for clients.

Basic Information

Product Name	Glycylglycinamide Hydrobromide
CAS No.	3479-49-0
Molecular Formula	C4H10BrN3O2
Molecular Weight	212.05 g/mol
Synonyms	Gly-Gly-NH2·HBr; Glycylglycine amide hydrobromide; H-Gly-Gly-NH2·HBr; Diglycineamide hydrobromide; 2-[(2-Aminoacetyl)amino]acetamide hydrobromide; Glycylglycinamide HBr; N-(Aminoacetyl)glycinamide hydrobromide; Peptide Synthesis Building Block 3479-49-0
EINECS	Contact for details

Quality Control

Our Glycylglycinamide Hydrobromide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for use under cGMP guidelines for non-clinical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.