Description

5-Bromo-4-tert-butyl-6-chloropyrimidine is a high-purity halogenated pyrimidine building block essential for advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for creating functionalized polymers or liquid crystals with specific electronic properties.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	5-Bromo-4-tert-Butyl-6-Chloropyrimidine
CAS No.	3438-54-8
Molecular Formula	C8H10BrClN2
Molecular Weight	249.54 g/mol
Synonyms	4-tert-Butyl-5-bromo-6-chloropyrimidine; 6-Chloro-4-tert-butyl-5-bromopyrimidine; 5-Bromo-6-chloro-4-(1,1-dimethylethyl)pyrimidine; 4-(tert-Butyl)-5-bromo-6-chloropyrimidine; Pyrimidine, 5-bromo-4-(1,1-dimethylethyl)-6-chloro-; 5-Bromo-4-(tert-butyl)-6-chloropyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-tert-butyl-6-chloropyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) with full analytical data are provided to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.