Description

5-Bromo-6-tert-Butyl-4-Pyrimidinol is a versatile pyrimidine derivative, a key heterocyclic building block prized for its unique substitution pattern. This compound matters for its role as a crucial synthetic intermediate in the development of advanced pharmaceuticals and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Acts as a precursor for the development of organic electronic materials, ligands for catalysis, and specialty polymers.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes, enzyme inhibitors, and tool compounds for biological research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Bromo-6-tert-Butyl-4-Pyrimidinol
CAS No.	3438-51-5
Molecular Formula	C8H11BrN2O
Molecular Weight	231.09 g/mol
Synonyms	4(1H)-Pyrimidinol, 5-bromo-6-(1,1-dimethylethyl)-; 5-Bromo-6-tert-butylpyrimidin-4-ol; 6-tert-Butyl-5-bromopyrimidin-4-ol; 5-Bromo-6-(tert-butyl)-4-hydroxypyrimidine; 4-Hydroxy-5-bromo-6-tert-butylpyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-tert-Butyl-4-Pyrimidinol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.