Description

4-T-Butyl-6-Hydroxypyrimidine is a substituted pyrimidine derivative, a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a phenolic hydroxyl group and a sterically hindered tert-butyl substituent, makes it a valuable precursor for creating complex molecules with tailored properties. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by manufacturers of specialty chemicals and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its heterocyclic core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Advanced Material Research: Employed in the development of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies in academic and industrial labs.
• Specialty Fine Chemicals: Intermediate for the production of dyes, pigments, and other performance chemicals requiring specific molecular architectures.

Basic Information

Product Name	4-T-Butyl-6-Hydroxypyrimidine
CAS No.	3438-49-1
Molecular Formula	C8H12N2O
Molecular Weight	152.19 g/mol
Synonyms	4-tert-Butyl-6-hydroxypyrimidine; 6-Hydroxy-4-tert-butylpyrimidine; 4-(1,1-Dimethylethyl)-6-hydroxypyrimidine; 4-(tert-Butyl)-6-pyrimidinol; 6-Hydroxy-4-(tert-butyl)pyrimidine; NSC 403697; 4-Tert-butyl-6-hydroxypyrimidine
EINECS	Contact for details

Quality Control

Our 4-T-Butyl-6-Hydroxypyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency meet the high standards required for research and industrial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ISO guidelines where applicable for intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.