Description

(2S,3R,4R,5S)-2,3,4,5-Tetrahydroxy-6-Oxo-Hexanoic Acid is a high-purity, stereochemically defined organic acid derivative with significant utility in advanced chemical synthesis. This compound serves as a critical chiral building block and intermediate for the production of complex molecules in regulated industries. It is essential for research and manufacturing in the pharmaceutical, fine chemical, and life science sectors where precise stereochemistry and purity are paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in nucleoside and carbohydrate-based drug development.
• Biochemical Research: Used as a precursor or standard in enzymatic studies, metabolic pathway research, and the investigation of sugar acid chemistry.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex, polyfunctional molecules in asymmetric synthesis and medicinal chemistry.
• Cosmetic & Personal Care Actives: Potential intermediate for the development of advanced skin-active ingredients, such as polyhydroxy acid derivatives.
• Agrochemical Development: Can be utilized in the research and synthesis of novel, biologically active compounds for crop protection.

Basic Information

Product Name	(2S,3R,4R,5S)-2,3,4,5-Tetrahydroxy-6-Oxo-Hexanoic Acid
CAS No.	3402-98-0
Molecular Formula	C6H10O8
Molecular Weight	210.14 g/mol
Synonyms	D-Glucaric Acid; D-Glucosaccharide Acid; D-Saccharide Acid; (2S,3R,4R,5S)-Tetrahydroxy-6-oxohexanoic Acid; Glucaric Acid (D-form); L-Gularic Acid; Tetrahydroxyadipic Acid; 3402-98-0
EINECS	222-250-0

Quality Control

Our (2S,3R,4R,5S)-2,3,4,5-Tetrahydroxy-6-Oxo-Hexanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets exacting standards for research and industrial use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.