Description

α-Methyl-Dl-Serine is a non-proteinogenic amino acid derivative of serine, featuring a methyl group substitution at the α-carbon. This structural modification makes it a valuable chiral building block and intermediate in sophisticated organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and fine chemical sectors. The compound is recognized under the CAS registry number 3398-40-1.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in peptidomimetics and enzyme inhibitors.
• Biochemical Research: Used as a substrate or analog in enzymatic studies and metabolic pathway investigations to understand biological processes.
• Peptide Synthesis: Serves as a modified amino acid residue in the solid-phase and solution-phase synthesis of custom peptides for drug discovery and diagnostic applications.
• Agrochemical Development: Employed as an intermediate in the synthesis of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Acts as a precursor for the manufacture of specialty chemicals, including complex ligands, catalysts, and dyes.
• Academic & Industrial R&D: Fundamental material for method development and chemical research in universities and corporate laboratories.

Basic Information

Product Name	α-Methyl-Dl-Serine
CAS No.	3398-40-1
Molecular Formula	C4H9NO3
Molecular Weight	119.12 g/mol
Synonyms	2-Amino-2-methyl-3-hydroxypropanoic acid; DL-2-Amino-2-methylserine; (±)-2-Amino-2-methyl-3-hydroxypropanoic acid; 2-Methylserine; α-Methylserine; AMS; 3-Hydroxy-2-aminoisovaleric acid
EINECS	Contact for details

Quality Control

Our α-Methyl-Dl-Serine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.