Description

Boc-Gly-Osu CAS NO 3392-07-2 is a high-purity, protected amino acid derivative, specifically N-(tert-Butoxycarbonyl)glycine N-hydroxysuccinimide ester. This compound serves as a critical building block in peptide synthesis, offering a reactive active ester for efficient amide bond formation under mild conditions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences industries for the production of peptides, peptide conjugates, and other bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key reagent for the efficient incorporation of glycine with N-terminal Boc-protection into growing peptide chains.
• Solution-Phase Peptide Coupling: Used for fragment condensation and the synthesis of small peptides and peptide mimetics in solution.
• Bioconjugation: Facilitates the labeling and modification of proteins, antibodies, and other biomolecules by introducing a glycine linker.
• Prodrug Synthesis: Employed in the design and synthesis of prodrugs where a peptide sequence is used for targeted drug release.
• Chemical Biology Research: Essential for preparing peptide-based probes, inhibitors, and tools for studying biological processes.
• API Intermediate Manufacturing: Serves as a critical raw material in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	Boc-Gly-Osu
CAS No.	3392-07-2
Molecular Formula	C11H16N2O6
Molecular Weight	272.25 g/mol
Synonyms	N-(tert-Butoxycarbonyl)glycine N-hydroxysuccinimide ester; N-Boc-glycine N-hydroxysuccinimide ester; N-α-Boc-glycine N-hydroxysuccinimide ester; Boc-Gly-OSu; Boc-Glycine-OSu; (2,5-Dioxopyrrolidin-1-yl) 2-[(tert-butoxycarbonyl)amino]acetate; 2-[(tert-Butoxycarbonyl)amino]acetic acid 2,5-dioxopyrrolidin-1-yl ester
EINECS	Contact for details

Quality Control

Our Boc-Gly-Osu is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.