Description

Nalidixic Acid Sodium Salt is the sodium salt derivative of the first-generation quinolone antibiotic, nalidixic acid. This compound serves as a crucial pharmaceutical intermediate and a reference standard in analytical and research settings. It is primarily utilized by manufacturers and research institutions in the pharmaceutical, biotechnology, and life science sectors for the development and quality control of antibacterial agents.

Application

• Pharmaceutical Intermediate: A key starting material or precursor in the synthesis of advanced quinolone and fluoroquinolone antibiotic compounds.
• Analytical Reference Standard: Used in high-performance liquid chromatography (HPLC), mass spectrometry, and other analytical methods for method development, validation, and quality assurance testing of related pharmaceutical products.
• Microbiological Research: Employed in laboratory studies to investigate the mechanism of action, resistance patterns, and efficacy of quinolone-class antibacterial agents.
• Active Pharmaceutical Ingredient (API) Manufacturing: Serves as a critical component in the production of specific antibiotic formulations, subject to strict Good Manufacturing Practice (GMP) guidelines.
• Biochemical Research: Utilized in studies targeting bacterial DNA gyrase and topoisomerase IV enzymes to understand and develop novel antibacterial therapies.

Basic Information

Product Name	Nalidixic Acid Sodium Salt
CAS No.	3374-05-8
Molecular Formula	C12H11N2NaO3
Molecular Weight	254.22 g/mol
Synonyms	Nalidixate Sodium; Sodium Nalidixate; 1-Ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid sodium salt; 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid sodium salt; Win 18,320 (sodium salt); Nalidixic Acid Na Salt; Negram (sodium salt); Nalidixic Acid Sodium
EINECS	222-161-2

Quality Control

Our Nalidixic Acid Sodium Salt is produced and tested under a rigorous quality management system. Each batch is analyzed to meet high-purity standards suitable for pharmaceutical intermediate and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0% (anhydrous basis)
Water Content (KF)	≤5.0%
pH (5% solution)	7.0 - 9.0
Heavy Metals (as Pb)	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.