Description

5-Acetoxy-1H-Pyrimidine-2,4-Dione is a key pyrimidine derivative, serving as a versatile acetylated intermediate in advanced organic synthesis. Its primary value lies in enabling precise chemical modifications for the development of novel active pharmaceutical ingredients (APIs) and nucleoside analogs. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty fine chemical sectors seeking to build complex heterocyclic structures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Agrochemical Research: Used in developing new generations of herbicides and plant growth regulators based on modified pyrimidine cores.
• Biochemical Probe Synthesis: Employed to create labeled or modified nucleobases for studying enzymatic mechanisms and metabolic pathways.
• Fine Chemical Production: Serves as a precursor for specialty chemicals used in material science and advanced polymer research.
• Academic & Contract Research: A valuable reagent for organic chemistry research in universities and CROs (Contract Research Organizations) exploring heterocyclic chemistry.

Basic Information

Product Name	5-Acetoxy-1H-Pyrimidine-2,4-Dione
CAS No.	3328-20-9
Molecular Formula	C6H6N2O4
Molecular Weight	170.12 g/mol
Synonyms	5-Acetoxyuracil; 5-Acetyloxy-1H-pyrimidine-2,4-dione; 5-Acetoxy-2,4(1H,3H)-pyrimidinedione; 5-O-Acetyluracil; 2,4-Dihydroxy-5-acetoxypyrimidine; NSC 52325; Uracil, 5-acetoxy-
EINECS	Contact for details

Quality Control

Our 5-Acetoxy-1H-Pyrimidine-2,4-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.