Description

D-Phe-L-Leu-Oh CAS NO 3303-56-8 is a high-purity dipeptide derivative, specifically the C-terminal carboxylic acid of phenylalanine-leucine. This compound serves as a critical building block and intermediate in advanced organic synthesis and peptide research. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require precise, high-quality chiral precursors for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of more complex peptide-based active pharmaceutical ingredients (APIs) and prodrugs.
• Peptide Chemistry Research: Used as a protected dipeptide fragment in solid-phase and solution-phase peptide synthesis (SPPS) to construct longer peptide chains.
• Biochemical Tool Development: Employed in the design and study of enzyme substrates, inhibitors, and receptor ligands due to its specific amino acid sequence.
• Cosmetic Peptide Synthesis: Acts as a precursor for bioactive peptides used in advanced skincare and cosmetic formulations.
• Academic & Industrial R&D: Serves as a standard or starting material in laboratories focused on medicinal chemistry and structural biology.

Basic Information

Product Name	D-Phe-L-Leu-Oh
CAS No.	3303-56-8
Molecular Formula	C15H22N2O3
Molecular Weight	278.35 g/mol
Synonyms	D-Phenylalanyl-L-leucine; (2R)-2-[[(2S)-2-Amino-4-methylpentanoyl]amino]-3-phenylpropanoic acid; H-D-Phe-L-Leu-OH; D-Phe-Leu; Phenylalanine-leucine dipeptide; D-Phenylalanine-L-leucine; Leu-Phe (reverse sequence variant)
EINECS	Contact for details

Quality Control

Our D-Phe-L-Leu-Oh is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the stringent requirements for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.