Description

Z-Asn-Onp is a protected amino acid derivative, specifically N-(p-Nitrophenoxycarbonyl)-L-asparagine, widely used as a key building block in peptide synthesis. This compound matters for its role in facilitating the controlled and efficient formation of peptide bonds, particularly in solid-phase peptide synthesis (SPPS) methodologies. Pharmaceutical researchers, biotech companies, and fine chemical manufacturers need it for the development of novel therapeutic peptides, research biochemicals, and other high-value synthetic targets.

Application

• Solid-Phase Peptide Synthesis (SPPS): A crucial reagent for the stepwise assembly of peptide chains, offering excellent coupling efficiency.
• Solution-Phase Peptide Synthesis: Used in traditional synthetic routes for producing custom peptides and peptide fragments.
• Pharmaceutical Intermediate: Serves as a key intermediate in the research and development of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: Employed in the chemical modification of proteins, antibodies, and other biomolecules for drug delivery and diagnostic applications.
• Research & Development: Essential for academic and industrial laboratories focused on medicinal chemistry, biochemistry, and proteomics research.
• Production of Protected Dipeptides and Oligopeptides: Used to construct specific peptide sequences with the asparagine side chain protected.

Basic Information

Product Name	Z-Asn-Onp
CAS No.	3256-57-3
Molecular Formula	C18H17N3O8
Molecular Weight	403.35 g/mol
Synonyms	Nα-Carbobenzyloxy-Nβ-(p-nitrophenoxycarbonyl)-L-asparagine; Z-L-Asparagine p-nitrophenyl ester; Z-Asn-ONp; Cbz-Asn-ONp; N-CBZ-L-Asparagine 4-Nitrophenyl Ester; (2S)-4-[[(4-Nitrophenoxy)carbonyl]amino]-2-[(phenylmethoxy)carbonylamino]-4-oxobutanoic Acid; Benzyl N-[(2S)-1,4-dihydro-1-[(4-nitrophenoxy)carbonyl]-4-oxo-2-(phenylmethoxy)carbonyl]asparaginate
EINECS	Contact for details

Quality Control

Our Z-Asn-Onp is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) detailing specific batch results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.