Description

H-Ala-His-Oh is a high-purity dipeptide derivative consisting of alanine and histidine residues. This compound serves as a crucial building block and intermediate in advanced pharmaceutical research and peptide synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and life science sectors for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of complex peptides and peptidomimetics with potential therapeutic activity.
• Biochemical Research: Used as a standard or reagent in enzymatic studies, metabolic pathway analysis, and protein structure-function research.
• Cosmetic Peptide Synthesis: A precursor for bioactive peptides used in advanced skincare formulations for anti-aging and skin repair properties.
• Nutraceutical Development: Investigated for incorporation into specialized dietary supplements and functional foods due to its amino acid composition.
• Enzyme Substrate/Analogue: Acts as a substrate or inhibitor in studies of proteases and other histidine-involving enzymatic processes.
• Chemical Biology Tool: Employed in the development of probes and labeled compounds for cellular imaging and diagnostic applications.

Basic Information

Product Name	H-Ala-His-Oh
CAS No.	3253-17-6
Molecular Formula	C9H14N4O3
Molecular Weight	226.23 g/mol
Synonyms	L-Alanyl-L-histidine; Ala-His; H-Ala-His-OH; Alanylhistidine; L-α-Alanyl-L-histidine; NSC 334365; 2-[(2-Amino-1-hydroxypropylidene)amino]-3-(1H-imidazol-5-yl)propanoic acid; (S)-2-((S)-2-Aminopropanamido)-3-(1H-imidazol-4-yl)propanoic acid
EINECS	221-857-3

Quality Control

Our H-Ala-His-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.