Description

Ac-Ser-Gly-Oh is a protected tripeptide derivative, specifically the acetylated form of the Ser-Gly dipeptide with a free carboxylic acid terminus. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), where it is used to introduce the Ser-Gly sequence while protecting the serine side chain from unwanted reactions. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers engaged in the development of therapeutic peptides, biochemical probes, and complex organic molecules.

Application

• Pharmaceutical Intermediates: Key raw material in the synthesis of longer, biologically active peptide sequences for drug discovery and development.
• Biochemical Research: Used as a standard or reagent in studies involving peptide structure, function, and metabolism.
• Solid-Phase Peptide Synthesis (SPPS): An essential protected fragment for the controlled, sequential assembly of peptides on a resin.
• Combinatorial Chemistry: Building block for creating diverse peptide libraries used in high-throughput screening for drug candidates.
• Glycopeptide Synthesis: Serves as a precursor where the serine residue can be further modified, for instance, in O-glycosylation reactions.
• Cosmetic Peptides: Potential intermediate in the production of bioactive peptides for skincare and cosmetic formulations.

Basic Information

Product Name	Ac-Ser-Gly-Oh
CAS No.	3244-65-3
Molecular Formula	C7H12N2O5
Molecular Weight	204.18 g/mol
Synonyms	Acetyl-L-seryl-glycine; N-Acetyl-L-serylglycine; N-Acetylserylglycine; Ac-Ser-Gly-OH; Ac-S-G-OH; L-Serine, N-acetyl-, glycyl-; Acetylserineglycine; NSC 334380
EINECS	221-826-8

Quality Control

Our Ac-Ser-Gly-Oh is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a desiccated environment to prevent absorption of moisture, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.