Description

Z-Ala-Gly-Oh is a protected dipeptide building block featuring a benzyloxycarbonyl (Z) N-terminal protecting group. This compound is essential for the controlled, stepwise synthesis of longer peptide chains in solid-phase and solution-phase methodologies. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide drug discovery, development, and production.

Application

• Peptide Synthesis: A fundamental building block (Z-protected dipeptide) for the controlled elongation of peptide sequences in both research and commercial-scale production.
• Pharmaceutical Intermediates: Serves as a key intermediate in the synthesis of complex therapeutic peptides and peptidomimetics targeting various diseases.
• Biochemical Research: Used in academic and industrial laboratories to study peptide structure-activity relationships (SAR) and enzyme-substrate interactions.
• Combinatorial Chemistry: Employed in the generation of diverse peptide libraries for high-throughput screening in drug discovery programs.
• Protease Substrate Analog: Can be utilized as a substrate or inhibitor analog in enzymatic studies to investigate protease specificity and mechanism.
• Material Science: Potential use in the development of bio-inspired materials and peptide-based polymers.

Basic Information

Product Name	Z-Ala-Gly-Oh
CAS No.	3235-17-4
Molecular Formula	C₁₃H₁₆N₂O₅
Molecular Weight	280.28 g/mol
Synonyms	N-(Benzyloxycarbonyl)-L-alanylglycine; Z-L-Ala-Gly-OH; Cbz-Ala-Gly-OH; N-Carbobenzoxy-L-alanylglycine; Nα-Cbz-L-alanylglycine; Benzyl N-[(2S)-1-[(carboxymethyl)amino]-1-oxopropan-2-yl]carbamate; (S)-2-(((Benzyloxy)carbonyl)amino)propanoic acid; L-Alanine, N-[(benzyloxy)carbonyl]-, glycyl-
EINECS	221-787-4

Quality Control

Our Z-Ala-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation by IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (L-isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.