Description

(S)-(+)-2-Amino-2-Methylbutanedioic Acid is a high-purity, non-proteinogenic amino acid derivative of significant interest in advanced chemical synthesis. This chiral building block is valued for its role in constructing complex molecular architectures with precise stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel therapeutic compounds and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in the synthesis of modified peptides and peptide mimetics to enhance stability, bioavailability, or biological activity.
• Asymmetric Synthesis: Serves as a valuable starting material or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Fine Chemical Production: Integral to the manufacture of high-value specialty chemicals, including flavors, fragrances, and advanced materials.
• Agrochemical Development: Used in the research phase for creating new chiral agrochemicals with targeted activity.

Basic Information

Product Name	(S)-(+)-2-Amino-2-Methylbutanedioic Acid
CAS No.	3227-17-6
Molecular Formula	C5H9NO4
Molecular Weight	147.13 g/mol
Synonyms	(S)-2-Amino-2-methylsuccinic acid; (S)-(+)-2-Amino-2-methylbutanedioic acid; (S)-2-Methylaspartic acid; L-2-Methylaspartic acid; (2S)-2-Amino-2-methylbutanedioic acid; 2-Amino-2-methyl-(S)-butanedioic acid; (S)-α-Methylaspartic acid
EINECS	221-757-4

Quality Control

Our (S)-(+)-2-Amino-2-Methylbutanedioic Acid is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.