Description

n-γ-L-Glutamyl-4-Aminobutyric Acid is a specialized dipeptide derivative, also known as γ-glutamyl-GABA, formed from L-glutamic acid and γ-aminobutyric acid (GABA). This compound is valued for its potential role in modulating neurotransmitter systems and as a biochemical precursor in specialized synthesis. It is primarily sought by research institutions and manufacturers in the pharmaceutical, nutraceutical, and biochemical research sectors for developing novel therapeutic agents and studying metabolic pathways.

Application

• Pharmaceutical Intermediate: Used in the research and development of novel neuroactive drugs and prodrugs targeting GABAergic systems.
• Biochemical Research: Serves as a key reagent and standard in studies of glutamyl transpeptidase activity, amino acid transport, and neurotransmitter metabolism.
• Nutraceutical Formulation: Investigated for potential inclusion in advanced dietary supplements aimed at cognitive support and stress management.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, and other chromatographic methods.
• Cosmeceutical Research: Explored for potential applications in topical formulations targeting skin barrier function and neuro-sensitive skin conditions.

Basic Information

Product Name	n-γ-L-Glutamyl-4-Aminobutyric Acid
CAS No.	3183-72-0
Molecular Formula	C₉H₁₆N₂O₆
Molecular Weight	248.23 g/mol
Synonyms	γ-L-Glutamyl-γ-aminobutyric acid; γ-Glutamyl-GABA; L-γ-Glutamyl-γ-aminobutyric acid; 4-[(4-Aminobutanoyl)amino]-5-amino-5-oxopentanoic acid; NSC 113986; Glutamyl-GABA; GABA-Glutamate conjugate
EINECS	221-690-3

Quality Control

Our n-γ-L-Glutamyl-4-Aminobutyric Acid is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.