Description

n-(2-Methylpropyl)Glycine CAS NO 3182-85-2 is a non-proteinogenic amino acid derivative featuring an isobutyl side chain, offering unique steric and chemical properties. This compound serves as a crucial building block and chiral intermediate in advanced organic synthesis, enabling the creation of complex molecular architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and peptide synthesis sectors for developing novel active ingredients and biochemical tools.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in protease inhibitor design.
• Peptide Synthesis: Used as a modified amino acid residue to introduce steric bulk and alter the conformational properties, stability, and bioavailability of synthetic peptides.
• Biochemical Research: Employed in enzymology studies as a substrate analog or inhibitor to probe enzyme active sites and mechanisms.
• Ligand Synthesis: Acts as a precursor for chelating agents and ligands in catalysis and metal coordination chemistry.
• Agrochemical Development: Serves as an intermediate in the synthesis of specialized herbicides and plant growth regulators with tailored activity.
• Material Science: Incorporated into specialty polymers and dendrimers to modify material properties such as solubility and thermal stability.

Basic Information

Product Name	n-(2-Methylpropyl)Glycine
CAS No.	3182-85-2
Molecular Formula	C6H13NO2
Molecular Weight	131.17 g/mol
Synonyms	2-Amino-4-methylpentanoic acid; 2-Amino-4-methylvaleric acid; 4-Methylnorvaline; DL-4-Methylnorvaline; Isobutylglycine; 2-Amino-4-methyl-pentanoic acid; α-Aminoisocaproic acid; (RS)-2-Amino-4-methylpentanoic acid
EINECS	221-693-5

Quality Control

Our n-(2-Methylpropyl)Glycine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric composition. We provide full traceability and detailed Certificates of Analysis (COA) upon request, ensuring compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Specify: DL, D, or L form available
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.