Description

6-Chloro-5-Nitro-4(1H)-Pyrimidinone is a versatile and high-value heterocyclic building block, primarily used as a key intermediate in the synthesis of complex organic molecules. Its unique structure, featuring both chloro and nitro substituents on the pyrimidinone core, makes it a critical precursor for introducing specific functional groups in target compounds. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a key starting material for the manufacture of dyes, pigments, and other specialty chemicals.
• Academic & Contract Research: Employed in organic synthesis research for developing new methodologies and creating complex molecular libraries.
• Material Science: Investigated as a precursor for the development of advanced organic electronic materials and polymers.

Basic Information

Product Name	6-Chloro-5-Nitro-4(1H)-Pyrimidinone
CAS No.	3137-56-2
Molecular Formula	C4H2ClN3O3
Molecular Weight	175.53 g/mol
Synonyms	5-Nitro-6-chloro-4(1H)-pyrimidinone; 6-Chloro-5-nitropyrimidin-4(1H)-one; 4(1H)-Pyrimidinone, 6-chloro-5-nitro-; 6-Chloro-5-nitro-1H-pyrimidin-4-one; 6-Chloro-5-nitro-4-hydroxypyrimidine; 5-Nitro-6-chloro-4-hydroxypyrimidine; 6-Chloro-5-nitropyrimidin-4-ol
EINECS	221-540-0

Quality Control

Our 6-Chloro-5-Nitro-4(1H)-Pyrimidinone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), related substances, and residual solvents. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.