Description

n-Acetyl Aspartyl-Glutamic Acid is a specialized dipeptide derivative of significant interest in advanced biochemical research and development. This compound serves as a crucial building block and a model substrate for studying enzymatic processes, neurochemistry, and peptide-based therapeutics. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in neuroscience, metabolic pathway analysis, and high-purity peptide synthesis.

Application

• Neuroscience Research: Used as a biochemical tool and reference standard in studies related to N-acetylaspartylglutamate (NAAG) metabolism and its role in the nervous system.
• Pharmaceutical Intermediates: Serves as a key synthetic precursor or intermediate in the development of novel peptide-based drugs and diagnostic agents.
• Enzymology Studies: Acts as a specific substrate for investigating the activity and inhibition of enzymes like glutamate carboxypeptidase II (GCPII).
• Biochemical Reagents: Employed in the formulation of high-purity reagents for cell culture media and in vitro diagnostic assays.
• Metabolic Pathway Analysis: Utilized in tracer studies and metabolic profiling to understand acetylated amino acid and dipeptide functions.
• Reference Standard: Provides a certified reference material for quality control and analytical method development in pharmaceutical and academic laboratories.

Basic Information

Product Name	n-Acetyl Aspartyl-Glutamic Acid
CAS No.	3106-85-2
Molecular Formula	C11H16N2O8
Molecular Weight	304.25 g/mol
Synonyms	N-Acetyl-L-aspartyl-L-glutamic acid; NAAG; Ac-Asp-Glu-OH; N-Acetyl-Asp-Glu; L-N-Acetylaspartylglutamic acid; N-Acetyl-α-L-aspartyl-L-glutamic acid; N-Acetyl-1-aspartylglutamic acid; N-Acetyl-L-α-aspartyl-L-glutamic acid
EINECS	221-457-6

Quality Control

Our n-Acetyl Aspartyl-Glutamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]D20: Specific range provided on COA
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.