Description

1-(Chloromethyl)-4-Fluoronaphthalene is a versatile halogenated naphthalene derivative that serves as a key synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both chloromethyl and fluoro substituents, makes it a valuable building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting specific biological receptors.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluoronaphthalene core contributes to biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Intermediate: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to introduce the naphthalene scaffold into more complex structures.
• Fluorescent Probe Development: The fluoronaphthalene moiety can be utilized in the design and synthesis of fluorescent dyes and molecular probes for biochemical sensing and imaging.

Basic Information

Product Name	1-(Chloromethyl)-4-Fluoronaphthalene
CAS No.	3094-25-5
Molecular Formula	C11H8ClF
Molecular Weight	194.63 g/mol
Synonyms	4-Fluoro-1-(chloromethyl)naphthalene; 1-Chloromethyl-4-fluoronaphthalene; 4-Fluoronaphthalen-1-ylmethyl chloride; (4-Fluoronaphthalen-1-yl)methyl chloride; 1-(Chloromethyl)-4-fluoronaphthalene; 3094-25-5; 4-Fluoro-1-naphthalenemethyl chloride
EINECS	Contact for details

Quality Control

Our 1-(Chloromethyl)-4-Fluoronaphthalene is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your quality assurance records.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.