Description

Z-Gly-Ala-Oh is a protected dipeptide building block, specifically the benzyloxycarbonyl (Z) derivative of the glycyl-alanine dipeptide. This compound is a fundamental intermediate in solid-phase peptide synthesis (SPPS), enabling the controlled and sequential construction of complex peptide chains. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the automated or manual synthesis of custom peptides.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation: Serves as a linker or spacer molecule in the creation of peptide-protein or peptide-small molecule conjugates.
• Biochemical Tool Development: Employed in the production of enzyme substrates, inhibitors, and standards for analytical assays.
• Academic & Industrial R&D: A fundamental reagent for studying peptide structure, function, and metabolism in laboratory settings.

Basic Information

Product Name	Z-Gly-Ala-Oh
CAS No.	3079-63-8
Molecular Formula	C13H16N2O5
Molecular Weight	280.28 g/mol
Synonyms	N-Carbobenzoxy-glycyl-L-alanine; N-Cbz-Glycyl-L-alanine; Z-Gly-L-Ala-OH; Benzyloxycarbonylglycyl-L-alanine; Cbz-Gly-Ala-OH; Nα-[(Benzyloxy)carbonyl]glycyl-L-alanine; N-Carbobenzyloxy-glycyl-L-alanine; L-Alanine, N-[(phenylmethoxy)carbonyl]glycyl-
EINECS	221-369-2

Quality Control

Our Z-Gly-Ala-Oh is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability for your research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	-20.0° to -24.0° (c=1 in AcOH)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.