Description

n-Acetyl-L-Isoleucine is a chemically modified derivative of the essential branched-chain amino acid L-Isoleucine. This acetylation enhances its stability and bioavailability, making it a valuable intermediate and building block for advanced synthesis. It is primarily utilized in the pharmaceutical and nutraceutical industries for research, peptide synthesis, and as a precursor in metabolic studies.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel peptides and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in metabolic pathway studies and as a substrate for enzymatic reactions in laboratory settings.
• Nutraceutical Formulation: Investigated for use in specialized amino acid supplements and clinical nutrition products.
• Cosmetic Ingredients: Potential application in skin-care formulations for its role as a moisture-regulating amino acid derivative.
• Chemical Synthesis: Serves as a protected form of L-Isoleucine in complex organic and peptide synthesis processes.

Basic Information

Product Name	n-Acetyl-L-Isoleucine
CAS No.	3077-46-1
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	N-Acetyl-L-isoleucine; N-Acetylisoleucine; (2S,3S)-2-Acetamido-3-methylpentanoic acid; Ac-Ile-OH; L-Isoleucine, N-acetyl-; NSC 3349; N-Acetylisoleucine; Nalpha-Acetyl-L-isoleucine
EINECS	221-355-1

Quality Control

Our n-Acetyl-L-Isoleucine is manufactured under a quality management system and undergoes rigorous analytical testing to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, optical rotation, and impurity profiles. Specifications can be tailored to meet research-grade or pharmaceutical intermediate requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	+20° to +25° (c=1 in H2O)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.