Description

1,3-Dihydro-5-(2-Chlorophenyl)-2H-1,4-Benzodiozepin-2-One is a high-purity benzodiazepine derivative, a key structural motif in medicinal chemistry. This compound is valued for its role as a crucial pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily required by R&D laboratories and manufacturers in the pharmaceutical and fine chemical sectors for developing new active ingredients and reference standards.

Application

• Pharmaceutical Intermediate: A critical precursor in the research and synthesis of novel benzodiazepine-based therapeutic agents.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold for developing new drug candidates targeting the central nervous system.
• Reference Standard: Used in analytical laboratories as a high-purity standard for method development, validation, and quality control testing.
• Medicinal Chemistry Research: A key building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Research: Employed in studies investigating ligand-receptor interactions, particularly with GABA-A receptors.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	1,3-Dihydro-5-(2-Chlorophenyl)-2H-1,4-Benzodiozepin-2-One
CAS No.	3022-68-2
Molecular Formula	C15H11ClN2O2
Molecular Weight	286.71 g/mol
Synonyms	5-(2-Chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 2-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-5-(2-chlorophenyl)-; 5-(o-Chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 2-Chloro-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one; 5-(2-Chlorophenyl)-1H-1,4-benzodiazepin-2(3H)-one; 3022-68-2 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 1,3-Dihydro-5-(2-Chlorophenyl)-2H-1,4-Benzodiozepin-2-One is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.