Description

H-Val-Nh2 Hcl CAS NO 3014-80-0 is a high-purity, protected amino acid derivative, specifically the hydrochloride salt of H-Val-NH₂. This compound serves as a critical building block (synthon) in advanced organic synthesis, enabling the controlled construction of complex peptide chains and other bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and peptide synthesis sectors who require reliable, high-quality intermediates for drug discovery and development.

Application

• Peptide Synthesis: A key protected intermediate for the solid-phase and solution-phase synthesis of custom peptides and peptidomimetics.
• Pharmaceutical Research: Used in the research and development of new active pharmaceutical ingredients (APIs), particularly for metabolic and neurological targets.
• Bioconjugation: Acts as a linker or spacer molecule for attaching peptides to other biomolecules, polymers, or surfaces in diagnostic and therapeutic applications.
• Chemical Biology: Employed in the study of protein-protein interactions and enzyme mechanisms as a substrate analog or inhibitor precursor.
• Process Development: Serves as a standard or reference material for analytical method development and quality control in GMP manufacturing environments.

Basic Information

Product Name	H-Val-Nh2 Hcl
CAS No.	3014-80-0
Molecular Formula	C₅H₁₃ClN₂O
Molecular Weight	152.62 g/mol
Synonyms	L-Valinamide hydrochloride; Valinamide HCl; H-Val-NH₂•HCl; (S)-2-Amino-3-methylbutanamide hydrochloride; Valine amide hydrochloride; N-(tert-Butoxycarbonyl)-L-valinamide; Boc-Val-NH₂ HCl (common protected form); L-2-Amino-3-methylbutyramide hydrochloride
EINECS	221-142-5

Quality Control

Our H-Val-Nh2 Hcl is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support cGMP standards for applications requiring the highest level of quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	-15° to -20° (c=1 in H₂O)
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.