Description

5-Fluoro-1,3-Dimethyluracil is a fluorinated pyrimidine derivative, a key heterocyclic building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for creating more complex molecules with tailored biological and chemical properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antiviral and anticancer agents, leveraging the fluorinated uracil scaffold.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, where the fluorine atom enhances biological activity and stability.
• Nucleoside & Nucleotide Chemistry: Serves as a modified base analog for constructing specialized oligonucleotides for diagnostic and research applications.
• Fine Chemical Synthesis: Acts as a building block for creating complex heterocyclic compounds used in material science and specialty polymers.
• Biochemical Research: Employed in studies of enzyme inhibition and metabolic pathways due to its structural similarity to natural pyrimidines.

Basic Information

Product Name	5-Fluoro-1,3-Dimethyluracil
CAS No.	3013-92-1
Molecular Formula	C6H7FN2O2
Molecular Weight	158.13 g/mol
Synonyms	5-Fluoro-1,3-dimethylpyrimidine-2,4(1H,3H)-dione; 1,3-Dimethyl-5-fluorouracil; 5-Fluoro-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione; 5-F-DMU; FDMU; NSC 52325
EINECS	221-137-7

Quality Control

Our 5-Fluoro-1,3-Dimethyluracil is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.