Description

2-Amino-4-Fluorophenol is a versatile fluorinated aromatic amine intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both an amino and a hydroxyl group on a fluorinated benzene ring, makes it a critical building block for creating complex molecules. This compound is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drugs targeting the central nervous system, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Dye and Pigment Manufacturing: Serves as a building block for synthesizing specialized azo dyes and high-performance pigments, contributing to color fastness and unique optical properties.
• Liquid Crystal & OLED Materials: An important intermediate for creating fluorinated components in electronic display materials, improving charge transport and thermal stability.
• Polymer Modification: Employed to introduce functional amine and phenolic groups into polymer chains, enhancing properties like adhesion, UV resistance, and chemical compatibility.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination chemistry and developing novel heterocyclic compounds.

Basic Information

Product Name	2-Amino-4-Fluorophenol
CAS No.	399-97-3
Molecular Formula	C6H6FNO
Molecular Weight	127.12 g/mol
Synonyms	4-Fluoro-2-aminophenol; 2-Amino-4-fluorophenol; 4-Fluoro-2-hydroxyaniline; 2-Hydroxy-5-fluoroaniline; 5-Fluoro-2-aminophenol; 2-Amino-4-fluoro-1-hydroxybenzene; 1-Amino-3-fluoro-4-hydroxybenzene; 4-Fluoro-o-aminophenol
EINECS	206-937-7

Quality Control

Our 2-Amino-4-Fluorophenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C/59-77°F). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term preservation. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to light yellow or pink crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	138°C - 142°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.