Description

4-Amino-3-Fluorophenol is a versatile fluorinated aromatic amine intermediate of significant importance in advanced organic synthesis. Its molecular structure, featuring both an amino and a hydroxyl group on a fluorinated benzene ring, makes it a critical building block for creating complex molecules with tailored properties. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-cancer agents.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, pesticides, and fungicides, where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Dye and Pigment Manufacturing: Intermediate for producing specialized azo dyes and high-performance pigments requiring fluorinated structures for color fastness.
• Polymer Modification: Used to introduce functional groups into polymer chains, enhancing properties like thermal stability, solubility, and chemical resistance.
• Research & Development: Valuable reagent in academic and industrial R&D for exploring new fluorinated compounds and reaction pathways.

Basic Information

Product Name	4-Amino-3-Fluorophenol
CAS No.	399-95-1
Molecular Formula	C6H6FNO
Molecular Weight	127.12 g/mol
Synonyms	3-Fluoro-4-aminophenol; 4-Amino-3-fluorophenol; 3-Fluoro-4-hydroxyaniline; 4-Hydroxy-2-fluoroaniline; 2-Fluoro-4-aminophenol; 1-Amino-2-fluoro-4-hydroxybenzene; 4-Amino-3-fluorophenol (primary name); AFPH
EINECS	206-937-6

Quality Control

Our 4-Amino-3-Fluorophenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets the high standards required for fine chemical synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Melting Point	138 - 142 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.